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Recommendations issued for genotype-based codeine therapy

January 31, 2012
  • Advising on this article:
  • Mary W. Roederer

KEY POINT

Recommendations for using hepatic cytochrome P450 2D6 (CYP2D6) genotype test results can guide codeine dosing by predicting a patient’s therapeutic response to the drug.

SOURCES

Crews KR et al. Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for codeine therapy in the context of cytochrome P450 2D6 (CYP2D6) genotype. Clin Pharmacol Ther. 2012;91:321–26.

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